RNA Details
Disease Name
hypertensive renal injury
Tissue
kidney
RNA Symbol
mir-101a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay;
Target
TGF-betaRI
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFbeta/Smad3 and NF-KB signalling in a mus musculus model of hypertension
Year
2019
Function
miR-101a exhibited protective effects against hypertensive nephropathy via inhibiting TGF-beta/smad3 and NF-KB signalling pathways.